New England Patriots @ Seattle Seahawks (-3.5)

San Francisco 49ers vs Los Angeles Rams (-3.5)

Game played in Australia

Atlanta Falcons (+3.5) @ Pittsburgh Steelers

Baltimore Ravens (-3.5) @ Indianapolis Colts

Buffalo Bills (-1.5) @ Houston Texans

Chicago Bears (-2.5) @ Carolina Panthers

Cleveland Browns @ Jacksonville Jaguars (-7.5)

New Orleans Saints (+7) @ Detroit Lions

New York Jets @ Tennessee Titans (-1.5)

Tampa Bay Buccaneers @ Cincinnati Bengals (-3.5)

Arizona Cardinals @ Los Angeles Chargers (-10.5)

Green Bay Packers (+1.5) @ Minnesota Vikings

Miami Dolphins @ Las Vegas Raiders (-3.5)

Washington Commanders @ Philadelphia Eagles (-5.5)

Dallas Cowboys @ New York Giants (+2.5)

Denver Broncos (+3) @ Kansas City Chiefs